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Why We're Losing the War on Cancer (and how to win it) by Clifton Leaf, Fortune Magazine (Mar 22, 2004)

Cancer as an evolutionary and ecological process, Lauren M.F. Merlo, John W. Pepper, Brian J. Reid and Carlo C. Maley, Nature Reviews (Dec 2006)
Broad and comprehensive review of work to date. A good lay summary can be found here on ScienceDaily.

Cancer genome sequencing: the challenges ahead, Henry Heng, BioEssays, Vol 29, Issue 8, Pages 783-794
Evolutionary and complex systems principles must be incorporated into cancer research. Genome level more important than gene level in cancer progression.

Elimination of altered karyotypes by sexual reproduction preserves species identity, Henry Heng, Genome 50: 517-524 (2007)a
A landmark paper that reverses the long and widely held misconception that sexual reproduction increases heterogeneity over asexual. Heng shows just the opposite.

Cure: Scientific, Social, and Organizational Requirements for the Specific Cure of Cancer by Arnold Glazier, MD
A comprehensive treatise on the logical implications of a complex evolutionary view of cancer which outlines both the technical and non-technical prerequisites for a cure to be found.

Women's reproductive cancers in an evolutionary context by Eaton, S. B., Pike, M. C., Short, R. V., Lee, N. C., Trussell, J., Hatcher, R. A., Wood, J. W., Worthman, C. M., Jones, N. G., Konner, M. J. & et al. Q Rev Biol 69, 353-67 (1994).

Malignant tumors in two ancient populations: An approach to historical tumor epidemiology. by Nerlich, A. G., Rohrbach, H., Bachmeier, B. & Zink, A. Oncol Rep 16, 197-202 (2006).



cmaley
cmaley
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Adobe Portable Document Format eaton-ev-and-women-repro-CA.pdf (Adobe Portable Document Format - 2,046k)
posted by cmaley   May 30 2008, 5:49 PM EDT
Eaton et al. on women's reproductive cancers in developed and hunter gatherer societies
Adobe Portable Document Format Merlo_Pepper_et_al_2006_NRC.pdf (Adobe Portable Document Format - 649k)
posted by Rafe.Furst   Dec 3 2007, 12:54 PM EST
Cancer as an evolutionary and ecological process